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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
12.42
Human Site:
T2134
Identified Species:
21.03
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
T2134
K
T
I
Q
Q
L
E
T
V
L
G
E
P
L
Q
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
T2134
K
T
I
Q
Q
L
E
T
V
L
G
E
P
L
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
A2131
K
T
I
Q
Q
L
E
A
I
L
G
E
P
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
A2133
K
T
I
Q
Q
L
E
A
V
L
G
E
P
L
Q
Rat
Rattus norvegicus
NP_001101888
2143
241191
A2133
T
T
I
Q
Q
L
E
A
V
L
G
E
P
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
V2145
K
T
I
Q
Q
L
E
V
I
L
G
E
P
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
T2149
K
V
I
Q
E
M
E
T
I
L
G
E
P
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
T2086
T
G
V
Q
E
L
E
T
I
L
G
E
S
V
Q
Honey Bee
Apis mellifera
XP_393800
2028
231830
E2018
N
A
V
R
T
L
E
E
I
L
G
E
P
L
Q
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
E1641
S
L
Q
H
K
F
G
E
T
F
W
S
G
G
S
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
D1626
A
L
L
H
K
A
Y
D
V
L
D
K
M
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
E1991
D
I
I
K
Q
M
E
E
M
S
G
E
S
L
A
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
L1760
V
K
V
V
E
N
V
L
G
E
P
F
D
R
Y
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
L1779
I
V
G
I
E
E
T
L
G
E
S
L
D
N
M
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
86.6
N.A.
N.A.
86.6
N.A.
73.3
N.A.
53.3
53.3
0
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
N.A.
93.3
N.A.
93.3
N.A.
80
73.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
40
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
60
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
22
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
8
0
15
0
0
% D
% Glu:
0
0
0
0
29
8
72
22
0
15
0
72
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
8
8
0
0
0
8
0
15
0
72
0
8
8
0
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
58
8
0
0
0
0
36
0
0
0
0
0
0
% I
% Lys:
43
8
0
8
15
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
15
8
0
0
58
0
15
0
72
0
8
0
65
8
% L
% Met:
0
0
0
0
0
15
0
0
8
0
0
0
8
0
8
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
58
0
0
% P
% Gln:
0
0
8
58
50
0
0
0
0
0
0
0
0
0
65
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
8
8
8
15
8
8
% S
% Thr:
15
43
0
0
8
0
8
29
8
0
0
0
0
0
0
% T
% Val:
8
15
22
8
0
0
8
8
36
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _